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They should also not be used by people with certain health conditions, such as severe high blood pressure, heart disease, diabetes, and those who are epileptic or who experience seizures
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Subsequently, an approach based on such methods, including an assessment of nicotine PK and subjective effects, has been used to determine the abuse liability of several e-cigarettes (e.g., 13,14,37,38,39,40 )
Cigarette smoking has halved since 2007, when daily smokers made up 22 percent of the population
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